The FANCB Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to FA2, FAB, and FANCB. This antibody recognizes Human antigen. The FANCB Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
The Fanconi anemia complementation group (FANC) currently
includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2,
FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM
and FANCN (also called PALB2). The previously defined group FANCH
is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability,
hypersensitivity to DNA crosslinking agents, increased chromosomal
breakage, and defective DNA repair. The members of the Fanconi
anemia complementation group do not share sequence similarity; they
are related by their assembly into a common nuclear protein
complex. This gene encodes the protein for complementation group B.
Alternative splicing results in two transcript variants encoding
the same protein